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1

Chemical regulation of epigenetic modifications: Opportunities for new cancer therapy

Yujun George Zheng, Jiang Wu, Ziyue Chen, Masha Goodman

Journal:

Medicinal Research Reviews

Year:

2008

Language:

english

File:

PDF, 486 KB

english, 2008

2

Fluorescent reporters of the histone acetyltransferase

Jiang Wu, Yujun George Zheng

Journal:

Analytical Biochemistry

Year:

2008

Language:

english

File:

PDF, 311 KB

english, 2008

3

Bisubstrate Inhibitors of the MYST HATs Esa1 and Tip60

Jiang Wu, Nan Xie, Zhikun Wu, Ying Zhang, Yujun George Zheng

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 266 KB

english, 2009

4

A Transient Kinetic Analysis of PRMT1 Catalysis

Feng, You, Xie, Nan, Jin, Miyeong, Stahley, Mary R., Stivers, James T., Zheng, Yujun George

Journal:

Year:

2011

Language:

english

File:

PDF, 1.40 MB

english, 2011

5

Two distinct aquaporin-4 cDNAs isolated from medullary cone of quail kidney

Yimu Yang, Yujun Cui, Zheng Fan, George A. Cook, Hiroko Nishimura

Journal:

Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology

Year:

2007

Language:

english

File:

PDF, 1.19 MB

english, 2007

6

Inhibitory study of protein arginine methyltransferase 1 using a fluorescent approach

You Feng, Nan Xie, Jiang Wu, Chao Yang, Yujun George Zheng

Journal:

Biochemical and Biophysical Research Communications

Year:

2009

Language:

english

File:

PDF, 399 KB

english, 2009

7

Synthesis and evaluation of carbocyanine dyes as PRMT inhibitors and imaging agents

Sinha, Sarmistha Halder, Owens, Eric A., Feng, You, Yang, Yutao, Xie, Yan, Tu, Yaping, Henary, Maged, Zheng, Yujun George

Journal:

European Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 1.76 MB

english, 2012

8

Discovery and Mechanistic Study of a Class of Protein Arginine Methylation Inhibitors

Feng, You, Li, Mingyong, Wang, Binghe, Zheng, Yujun George

Journal:

Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 1.64 MB

english, 2010

9

Labeling Lysine Acetyltransferase Substrates with Engineered Enzymes and Functionalized Cofactor Surrogates

Yang, Chao, Mi, Jiaqi, Feng, You, Ngo, Liza, Gao, Tielong, Yan, Leilei, Zheng, Yujun George

Journal:

Journal of the American Chemical Society

Year:

2013

Language:

english

File:

PDF, 610 KB

english, 2013

10

Comparative studies of thiol-sensitive fluorogenic probes for HAT assays

Tielong Gao, Chao Yang, Yujun George Zheng

Journal:

Analytical and Bioanalytical Chemistry

Year:

2013

Language:

english

File:

PDF, 830 KB

english, 2013

11

Diamidine Compounds for Selective Inhibition of Protein Arginine Methyltransferase 1

Yan, Leilei, Yan, Chunli, Qian, Kun, Su, Hairui, Kofsky-Wofford, Stephanie A., Lee, Wei-Chao, Zhao, Xinyang, Ho, Meng-Chiao, Ivanov, Ivaylo, Zheng, Yujun George

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 3.37 MB

english, 2014

12

A Dual-Mode Fluorescence Strategy for Screening HAT Modulators

Xie, Nan, Elangwe, Emilia N., Asher, Sabrina, Zheng, Yujun George

Journal:

Bioconjugate Chemistry

Year:

2009

Language:

english

File:

PDF, 339 KB

english, 2009

13

[IEEE 2008 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology (CIBCB 2008) - Sun Valley, ID, USA (2008.09.15-2008.09.17)] 2008 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology - Granular decision fusion systems for effective protein methylation pPrediction

Ding, Zejin Jason, Feng, You, Zheng, Yujun George, Zhang, Yan-Qing

Year:

2008

Language:

english

File:

PDF, 716 KB

english, 2008

14

[IEEE 2009 International Joint Conference on Bioinformatics, Systems Biology and Intelligent Computing - Shanghai, China (2009.08.3-2009.08.5)] 2009 International Joint Conference on Bioinformatics, Systems Biology and Intelligent Computing - Identifying New Methylated Arginines via Granular Decision Fusion with SVM Modeling

Ding, Zejin Jason, Zhang, Yan-Qing, Xie, Nan, Zheng, Yujun George

Year:

2009

Language:

english

File:

PDF, 1.21 MB

english, 2009

15

Labeling: Palladium brings proteins to life

Qian, Kun, Zheng, Yujun George

Journal:

Nature Chemical Biology

Year:

2014

Language:

english

File:

PDF, 709 KB

english, 2014

16

[IEEE 2009 IEEE International Conference on Systems, Man and Cybernetics - SMC - San Antonio, TX, USA (2009.10.11-2009.10.14)] 2009 IEEE International Conference on Systems, Man and Cybernetics - Feature selection and granular SVM classification for protein arginine methylation identification

Ding, Zejin, Zhang, Yan-Qing, Zheng, Yujun George

Year:

2009

Language:

english

File:

PDF, 243 KB

english, 2009

17

Exploration of Cyanine Compounds as Selective Inhibitors of Protein Arginine Methyltransferases: Synthesis and Biological Evaluation

Hu, Hao, Owens, Eric A., Su, Hairui, Yan, Leilei, Levitz, Andrew, Zhao, Xinyang, Henary, Maged, Zheng, Yujun George

Journal:

Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 5.44 MB

english, 2015

18

SYNTHESIS OF A COUMARIN-HISTONE CONJUGATE FOR HAT FLUORESCENT ASSAY

Chen, Ziyue, Zheng, Yujun George

Journal:

Heterocyclic Communications

Year:

2007

Language:

english

File:

PDF, 533 KB

english, 2007

19

Synthesis of H4 pantetheine adducts for histone acetyltransferase inhibition

Wu, Jiang, Zheng, Yujun George

Journal:

Heterocyclic Communications

Year:

2010

Language:

english

File:

PDF, 346 KB

english, 2010

20

SAM/SAH Analogues as Versatile Tools for SAM-dependent Methyltransferases

Zhang, Jing, Zheng, Yujun George

Journal:

ACS Chemical Biology

Year:

2015

Language:

english

File:

PDF, 825 KB

english, 2015

21

Design of a fluorescent ligand targeting the S-adenosylmethionine binding site of the histone methyltransferase MLL1

Luan, Yepeng, Blazer, Levi L., Hu, Hao, Hajian, Taraneh, Zhang, Jing, Wu, Hong, Houliston, Scott, Arrowsmith, Cheryl H., Vedadi, Masoud, Zheng, Yujun George

Journal:

Organic & Biomolecular Chemistry

Year:

2016

Language:

english

File:

PDF, 790 KB

english, 2016

22

Effective Quenchers Are Required to Eliminate the Interference of Substrate: Cofactor Binding in the HAT Scintillation Proximity Assay

Ngo, Liza, Wu, Jiang, Yang, Chao, Zheng, Yujun George

Journal:

Assay and Drug Development Technologies

Year:

2015

Language:

english

File:

PDF, 633 KB

english, 2015

23

Molecular Mechanism underlying PRMT1 Dimerization for SAM Binding and Methylase Activity

Zhou, Ran, Xie, Yiqian, Hu, Hao, Hu, Guang, Patel, Viral Sanjay, Zhang, Jin, Yu, Kunqian, Huang, Yiran, Jiang, Hualiang, Liang, Zhongjie, Zheng, Yujun George, Luo, Cheng

Journal:

Journal of Chemical Information and Modeling

Year:

2015

Language:

english

File:

PDF, 4.27 MB

english, 2015

24

PROTEIN ARGININE METHYLTRANSFERASE 8: tetrameric structure and protein substrate specificity

Lee, Wei-Chao, Lin, Wen-Ling, Matsui, Tsutomu, Chen, Eric S.-W., Wei, Tong-You Wade, Lin, Wen-Hsuan, Hu, Hao, Zheng, Yujun George, Tsai, Ming-Daw, Ho, Meng-Chiao

Journal:

Year:

2015

Language:

english

File:

PDF, 2.21 MB

english, 2015

25

Integration of Bioorthogonal Probes and Q-FRET for the Detection of Histone Acetyltransferase Activity

Han, Zhen, Luan, Yepeng, Zheng, Yujun George

Journal:

Year:

2015

Language:

english

File:

PDF, 657 KB

english, 2015

26

Effect of methylation on the side-chain p K a value of arginine

Evich, Marina, Stroeva, Ekaterina, Zheng, Yujun George, Germann, Markus W.

Journal:

Protein Science

Year:

2016

Language:

english

File:

PDF, 1.11 MB

english, 2016

27

A Suite of Biochemical Assays for Screening RNA Methyltransferase BCDIN3D

Blazer, Levi L., Li, Fengling, Kennedy, Steven, Zheng, Yujun George, Arrowsmith, Cheryl H., Vedadi, Masoud

Journal:

Journal of Biomolecular Screening

Year:

2016

Language:

english

File:

PDF, 1.13 MB

english, 2016

28

Discovery of decamidine as a new and potent PRMT1 inhibitor

Zhang, Jing, Qian, Kun, Yan, Chunli, He, Maomao, Jassim, Brenson A., Ivanov, Ivaylo, Zheng, Yujun George

Journal:

Year:

2017

Language:

english

File:

PDF, 2.43 MB

english, 2017

29

Histone Acetyltransferase Activity of MOF Is Required for MLL-AF9 Leukemogenesis

Valerio, Daria G., Xu, Haiming, Chen, Chun-Wei, Hoshii, Takayuki, Eisold, Meghan E., Delaney, Christopher, Cusan, Monica, Deshpande, Aniruddha J., Huang, Chun-Hao, Lujambio, Amaia, Zheng, YuJun George

Journal:

Cancer Research

Year:

2017

Language:

english

File:

PDF, 2.34 MB

english, 2017

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